Typical Materials and Formats

• Diverse Fluidic Materials such as glass (e.g., Schott D263), COC / COP, Polycarbonate, Acrylic, PET, PEEK, PFA, Teflon, Delrin, Stainless Steel (304 and 316), and more
• Diverse Surface Chemistries such as silanes, lo-bind polymers, click chemistry immobilization groups, and biotinylation
• Tubing / Manifold integration with microfluidic chips

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Standard Engineering Processes

Our engineering team moves fast to make your fluidic chips or system integration work exactly the way you need it to

• CNC milling of custom chips, devices, fixtures, and fluidic connectors
• CO2 laser for structuring of plastic materials
• Fiber laser for structuring and etching of metals
• UV laser for precision structuring of glass, plastic, and PSA
• 3D printing (both Vat photopolymerization and FDM extrusion) for rapid prototyping
• Multilayer Bonding with Pressure Sensitive Adhesive or UV Adhesive
• Liquid silicone molding of custom gaskets
• Laser Welding to bond layers of Plastics

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Standard Surface Chemistry Processes

Our surfaces team excels at both 2D and 3D surface modification, enabling low non-specific binding and/or stable biofunctionalization — directly integrated into your prototype or final part.

• Liquid Phase Bath Chemistry for scalable deposition of 2D (silane) and 3D (polymeric) coatings
• Oxygen/Argon/Water Plasma for rapid surface cleaning and activation
• Hydrogel Photopolymerization for generating 3D scaffolds and cell adhesion surfaces
• Chemical Vapor Deposition (coming soon) for ultra uniform high quality silane coatings
• Reactive Ion Etching (coming soon) for nanostructuring of polymers and glass
• UV/Ozone Cleaning & Activation (coming soon) for cleaning and hydroxylation of surfaces
• Spin Coating for precision application of thin films
• Vacuum Ovens for precision sample drying
• Fume Hoods and Laminar flow hoods for safe and clean chemical handling
• Robotic Liquid Handling for speed and precision
• Centrifuges for rapid separations

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Standard Metrology & Characterization Processes

We pride ourselves on measuring what matters. Quality starts with thoughtful metrics.

• Optical & Fluorescence Microscopy
• 2D & 3D Optical Dimensional CMM
• Flow Cell Gap Height & Flatness
• Surface Roughness
• Film Adhesion
• Fluidic Pressure, Flow, and Exchange
• Contact Angle

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Instrument and Software Integration

We make custom hardware, instrument control software, and UI to support the product development process in all phases.

• Custom 2D / 3D Gantries with laser-based measurement for R&D and Production Environments
• Custom Fluidic control systems, pumps, valves, and sensor feedback
• Python-based APIs and GUIs
• Microcontroller embedded software

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Why BioNexus?

• Deep scientific understanding of your needs. Experience across life science and diagnostics devices
• In-house fabrication for lighting speed iteration
• Highly interdisciplinary team
• Scalable workflows that get you to manufacturing with quality, faster
• Integration of fluidics and surface chemistry expertise
• Clever team that solves the toughest challenges at the interfaces between fields and needs